![]() ![]() Cognitive impairment occurs commonly among tramadol-abuse patients. There was no association between cognitive impairment and sociodemographic or clinical factors. Cognitive impairment was significantly associated with polysubstance abuse. Tramadol-alone patients were more than 2 times more likely to have cognitive impairment than control subjects (67% vs 28%). Tramadol-abuse patients were about 3 times more likely to have cognitive impairment than control subjects (81% vs 28%). Twenty-four percent of the cases used tramadol alone, whereas the remaining used tramadol and other substances, mainly cannabis (66%) and benzodiazepines (27%). The participants were interviewed using Montreal Cognitive Assessment test and had urine screening for drugs. Patients were divided into 2 groups: patients who used tramadol only ( tramadol-alone group) and patients who used tramadol and other substances (polysubstance group). This study included 100 patients with tramadol abuse and 100 control subjects (matched for age, sex, and education) who were recruited from Zagazig University Hospital, Egypt. The objective of this study was to estimate the prevalence and correlates of cognitive impairment among tramadol-abuse patients and control subjects. ![]() Tramadol abuse is a public health problem in Egypt. Cognitive Impairment and Tramadol Dependence.īassiony, Medhat M Youssef, Usama M Hassan, Mervat S Salah El-Deen, Ghada M El-Gohari, Hayam Abdelghani, Mohamed Abdalla, Ahmed Ibrahim, Dalia HĬognitive impairment is one of the consequences of substance abuse. ![]()
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